PEA protects against bacterial an infection through innate immune modulation involving MCs, macrophages and microglia. Prophylactic PEA in a dose of 0.one mg/kg body pounds prolonged survival amount and lessened neuro-inflammation in an aged murine bacterial meningitis model, within the absence of antibiotics [42].The anti‐inflammatory results of
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2005). These success weren't surprising if we take into account that PEA is usually a improperly drinking water‐soluble compound, which may Restrict its oral absorption and bioavailability, but they may also recommend a brief‐lived action of PEA, in arrangement with The truth that this compound is degraded by two different hydrolases, that's, N